From the South (Airport) 
I-95 North towards Baltimore. Take Exit 52 - Russell St. At the bottom of the ramp veer onto Russell St. M&T Bank Stadium will be on your right.
OR
I-295 North towards Baltimore. I-295 becomes Russell Street and the stadium will be on your right.

From the Northwest 
I-83 South (Baltimore) to Lombard Street and make a right. Then make a left (South) onto Greene Street, M&T Bank Stadium is on your left.

From the Northeast 
I-95 South through Ft. McHenry Tunnel. Take Exit 53 (I-395) North to MLK Blvd./Russell Street (right lane). Take first exit ramp (follow lighted signs). At the bottom of the ramp make a left onto Lee St. and turn left at the light onto Russell St. M&T Bank Stadium will be on your left.