WR Zay Flowers vs. Browns CB Denzel Ward: Offensive Coordinator Declan Doyle has moved Flowers all around Baltimore's formation, meaning that Flowers might line up against a few different Browns defenders. But Flowers and Ward, who are two of the best at their respective positions, still might see each other a lot, as Cleveland runs man coverage more than any other team in the NFL.

OLB Trey Hendrickson vs. Browns OT Spencer Fano: The No. 9 pick in this year's NFL Draft, Fano has started his rookie season strong but will face a tough test in blocking Hendrickson, who is set to return after missing Baltimore's last two games with a finger injury.

RB Derrick Henry vs. Browns Run Defense: The Browns rank No. 23 in yards per carry allowed and just gave up 116 yards and a touchdown to New York Jets backup running back Braelon Allen. Henry is coming off a 102-yard rushing performance against the Atlanta Falcons. He ran for 103 yards and a touchdown in Cleveland last season.

Ravens Offensive Line vs. Browns Pass Rush: The Browns are one of the NFL's best at pressuring the quarterback. Baltimore's offensive line has been in flux due to injuries early this season. How will it handle another change?

Head Coach Jesse Minter vs. Browns Head Coach Todd Monken: Minter and Monken have played huge roles in building high-octane offenses and defenses at multiple stops. Now in their first seasons as head coach, their chess match will be one to watch on Sunday.