CB Brandon Stephens vs. WR Ja'Marr Chase

Marlon Humphrey (calf) is doubtful to play. If he doesn't suit up, Stephens will be the Ravens' top cornerback going against Chase. The key with Chase is keeping him in front of you and getting him down quickly on the shorter receptions. He can break off big gains after the catch and had a 64-yard touchdown last week against the Texans. Stephens has done well not giving up big plays this season and that will have to continue.

LB Patrick Queen vs. QB Joe Burrow

College teammates at LSU will reunite once again on the primetime stage. Burrow is healthier than he was in the teams' Week 2 meeting, when a calf injury limited his mobility. The Ravens let Deshaun Watson get loose with his legs too many times last week and Burrow can do the same, either to run or throw. Queen will be part of the answer to keeping him contained, as well as a main player in changing up the picture from pre-snap to post-snap to make Burrow hesitate.

WR Zay Flowers vs. CB Mike Hilton

The Bengals like to play man-to-man coverage and Flowers has been roasting it this season. Hilton is one of the league's tougher shakes, however. The Ravens' rookie wide receiver is itching for a big game in his primetime debut, and he'll have a scrappy veteran to deal with.