Ravens LBs vs. RB Saquon Barkley

Barkley is on a heater coming off a game with more than 300 yards from scrimmage. He's the NFL's leading rusher but will face a strong Baltimore run defense that could get Roquan Smith back. Malik Harrison stepped up with a career-high 12 tackles with Smith out last week, and the Ravens will need solid play from the linebackers again to slow down Barkley.

CB Brandon Stephens vs. WR A.J. Brown

Brown is 12th in the NFL with 727 receiving yards, but he has played at least three fewer games than all but one player ahead of him. While Stephens isn't playing every snap anymore, he's still seeing the majority and is coming off one of his best games of the year. Baltimore's defense is coming off back-to-back strong games but has a massive test against Brown and Philadelphia.

WR Zay Flowers vs. CB Quinyon Mitchell

Flowers is on his way to his first 1,000-yard season, but he faces the potential Defensive Rookie of the Year on Sunday. Mitchell hasn't given up a touchdown all season and has only been targeted 10 times in the last four games, according to Pro Football Focus. Winning the Flowers-Mitchell matchup will play a big role in the outcome of the game.

C Tyler Linderbaum vs. DT Jalen Carter

Linderbaum has been the anchor in the middle of Baltimore's line, but he faces one of the best tackles in the league in Carter. While Carter didn't have a sack against the Rams last week, he dominated the game, drawing double teams as the rest of Philadelphia's pass rush feasted. Linderbaum and the rest of the Ravens offensive line must keep Carter in check to get the run game going.

QB Lamar Jackson vs. LB Nakobe Dean

Jackson leads the league in passing yards (3,053) and is tied for first in passing touchdowns (27) as he continues maybe the best season of his career. Philadelphia is No. 6 in scoring defense and has been even better the past few weeks. Dean has been stellar this season and will try to take away the middle of the field for Jackson and draw pressure on blitzes.