S Kyle Hamilton vs. QB Drake Maye

It's not often that a Defensive Player of the Year candidate squares off against a Most Valuable Player candidate, but that's what will happen Sunday night. Hamilton has been the driving force behind the Ravens' defensive turnaround this season, constantly disrupting offenses as a do-it-all box defender. In his second season, Maye has completed a league-best 70.9% of his passes for 3,567 yards, 23 touchdowns, and seven interceptions. With 362 rushing yards and four scores on the ground, Maye's athleticism will also be something Hamilton and the Ravens defense watch out for.

C Tyler Linderbaum vs. DT Christian Barmore

The Ravens' offensive line had one of its better games last week against the Bengals. The unit helped pave the way for 189 rushing yards while keeping Lamar Jackson relatively clean in the pocket. Linderbaum, Daniel Faalele, and Andrew Vorhees will share a tough assignment against Barmore, who leads New England with 49 pressures and is third among all defensive tackles in pressures, per Next Gen Stats.

ILB Roquan Smith vs. RB TreVeyon Henderson

Smith and the Ravens' run defense have bottled up rushers the last several weeks, most recently holding the Bengals to 3.4 yards per carry and the Steelers to 34 yards on the ground. Henderson gashed Buffalo last week with a career-high 148 yards and two touchdowns on 14 carries, highlighted by a 65-yard score. With Teddye Buchanan out for the season, Smith and third-year player Trenton Simpson will need to step up and contain Henderson.

WR Zay Flowers vs. CB Christian Gonzalez

Flowers needs just 41 receiving yards to hit the 1,000 mark for the second straight season. The Pro Bowl pass catcher has 31 more receptions and 600 more yards than any other receiver for Baltimore. Gonzalez gave up zero catches on three targets against the Bills last week. The Patriots' top defensive back will look to keep Flowers in check, something teams have struggled to accomplish at times this season.

OLB Tavius Robinson vs. LT Vederian Lowe

In his first game back from injury, Robinson made several impact plays against the Bengals, including a sack and a pressure that led to a game-clinching pick-six. After teeing off on Joe Burrow, Robinson and the Ravens' front seven will now square off against Maye, who has been sacked the fourth-most times in the league. Starting in place of injured first-round pick Will Campbell, Lowe has allowed pressures on 10.8% of his pass block reps.