CB Nate Wiggins vs. WR Ja'Marr Chase

Wiggins leads the team with three interceptions, and he'll have his work cut out for him on Thursday. In two games last season, Chase had a combined 21 catches, 457 yards, and five touchdowns. With Joe Burrow back in the lineup and with Chase coming off a one-game suspension, the Ravens could see a lot of passes thrown Chase's way. It'll be up to Wiggins and the Ravens' secondary to limit his big-play ability.

S Kyle Hamilton vs. QB Joe Burrow

Hamilton is set to play after going down with an ankle injury late in last week's game against the Jets. The All-Pro safety logged an estimated full practice Wednesday and carries no injury designation, which is good news for a Ravens defense that will have to contend with Burrow in his first game back from injury. Burrow, who hasn't played since Week 2, had circled Thursday's game as a possible return date. Hamilton and the Ravens' defense will aim to spoil that decision.

QB Lamar Jackson vs. LB Barrett Carter

Jackson has dealt with a different injury the last three weeks on top of missing three games due to a hamstring ailment earlier this season. The two-time MVP hasn't thrown a touchdown in the last two weeks, but could find his groove against a defense that has given up the most yards and points in the league. A fourth-round rookie, Carter has earned a starting spot and is tied for the third most tackles on the team. With his athleticism, Carter could also be a potential quarterback spy candidate to contain Jackson's rushing ability.

OLB Mike Green vs. LT Orlando Brown

Green had one of his best games against the Jets last week, finishing with five pressures, one sack, and the highest Pro Football Focus grade of his rookie season. The second-round pick will have a tough task going up against the 29-year-old Brown, a former Raven who will try to protect Burrow's blind side in his first game back.

ILB Roquan Smith vs. RB Chase Brown

Smith will play his fourth career Thanksgiving game, and in his first two with the Bears, he had a combined 27 tackles and three sacks. Can he have similar production against Brown, who had his most productive outing of the season last week with 107 rushing yards and 23 receiving yards? With Burrow possibly less mobile than usual, Brown could get a heavy load of touches against a Baltimore defense that was gashed by Jets running back Breece Hall (four catches, 75 yards) last week.