TE Mark Andrews vs. S Josh Metellus

Andrews can make history on Sunday as he is just 18 yards away from becoming the Ravens' all-time receiving leader. The veteran tight end caught two touchdowns last week and is Lamar Jackson's go-to target. A safety/linebacker hybrid, Metellus leads the Vikings with two interceptions this season. He and the Vikings' defense have been burned by opposing tight ends the past two games, creating a ripe opportunity for Andrews and the tight end room to make plays downfield.

LT Ronnie Stanley vs. OLB Jonathan Greenard

Stanley returned to the lineup the last few games and will have to protect Jackson's blindside against an aggressive Brian Flores-led defense. Greenard's two sacks this season won't blow away any box-score lookers, but the 28-year-old has been the most active pass rusher for Minnesota with a team-high 29 pressures, according to Next Gen Stats.

CB Nate Wiggins vs. WR Justin Jefferson

Matchups like the one against Jefferson are why the Ravens drafted Wiggins in the first round. The second-year cornerback already has two interceptions this season and has been vocal about guarding top weapons. Jefferson, who the Vikings move around all over the field, demands every bit of attention. He leads the team with 649 yards and two touchdowns on 47 receptions. Locking down Jefferson will be the top priority for Wiggins and Marlon Humphrey, but they also can't forget about Jordan Addison and the rest of Minnesota's playmakers.

S Kyle Hamilton vs. QB J.J. McCarthy

Since moving closer to the line of scrimmage on a full-time basis, Hamilton has elevated the entire Ravens defense. The All-Pro safety has been stout stopping the run and putting pressure on opposing quarterbacks. Hamilton will have plenty of opportunities to pressure and confuse McCarthy, who will make just his fourth career start. McCarthy scored three touchdowns in a win over Detroit last week, but his inexperience showed on several inaccurate throws, one of which led to an interception.

RB Derrick Henry vs. LB Eric Wilson

Henry has averaged 104 yards per game over the last three contests, and with Jackson back on the field, he could ramp up his production even more against Minnesota. The Vikings' defense held the Lions' rushing attack in check last week but has been gashed on several occasions this season. Wilson leads Minnesota in tackles and is also second on the team in sacks (3.5). He'll try to slow Henry down and could spy Jackson.