Ravens S Kyle Hamilton vs. Colts TE Tyler Warren, Week 1

Warren is one of the best young tight ends in the league. He led the Colts in targets (112) as a rookie and posted 817 yards and four touchdowns. Hamilton is a versatile tight end eraser who will also be called on to provide run support versus Jonathan Taylor.

Ravens CB Marlon Humphrey vs. Saints WR Jordyn Tyson, Week 2

The Saints picked up a high-flying rookie wide receiver in the first round to pair with Chris Olave, who posted 1,163 receiving yards last season. That duo will be a strong test for Baltimore's secondary.

Ravens CB Nate Wiggins vs. Cowboys WR CeeDee Lamb, Week 3

Wiggins' welcome to the NFL moment was facing off against Cowboys wide receiver CeeDee Lamb in 2024. Now entering Year 3, Wiggins has a chance to show how much he's grown.

Ravens G Vega Ioane vs. Titans DT Jeffrey Simmons, Week 4

The Titans defense is anchored by Simmons, a massive four-time Pro Bowler known for his nasty demeanor. That suits Ioane, who brings an edge to his blocking.

Ravens LB Roquan Smith vs. Falcons RB Bijan Robinson, Week 5

Robinson had the fourth-most rushing yards in the NFL last season and Atlanta will keep feeding him the rock. Robinson is a home-run threat that Smith must contain for a win.

Ravens LT Ronnie Stanley vs. Browns DE Myles Garrett, Week 6

Garrett had 5 ½ sacks against the Ravens in two games last year, which helped vault him to the NFL's single-season sack record. Garrett is extremely difficult to block, and it will be interesting to see what adjustments the Ravens make.

Ravens CB Nate Wiggins vs. Bengals WR Ja'Marr Chase, Week 7

Wiggins will look to become one of the NFL's top cornerbacks this season and he'll have a battle with one of the top wide receivers. In two games last season, Chase had 17 catches for 242 yards. He's been a major thorn in the Ravens' side.

Ravens QB Lamar Jackson vs. Bills QB Josh Allen, Week 8

They don't directly face each other, but whenever these star quarterbacks and MVPs square off, it's a must-see shootout that lives up to the billing.

Ravens WR Rashod Bateman vs. Jaguars CB Travis Hunter, Week 9

Hunter is reportedly making the switch from primarily being a wide receiver to majoring at cornerback. A premier route-runner, Bateman could give Hunter trouble on the perimeter.

Ravens S Kyle Hamilton vs. Chargers TE Charlie Kolar, Week 10

It's a battle of former teammates when Hamilton tries to blow up Kolar's blocks and stymie the Chargers' rushing attack. This will also be a Baltimore reunion for running back Keaton Mitchell, and Hamilton will be charged with not letting Mitchell break loose.

Ravens OLB Mike Green vs. Panthers RT Monroe Freeling, Week 11

The Ravens expect a breakout season from Green and he'll have a juicy matchup against the Panthers' rookie first-round pick.

Ravens WR Zay Flowers vs. Texans CB Derek Stingley Jr., Week 12

Flowers is one of the NFL's top receivers and Stingley is one of its premier cornerbacks. The Texans blew out the Ravens last season, 44-10, but Flowers had a team-high five catches for 72 yards.

Ravens OLB Trey Hendrickson vs. Buccaneers LT Tristan Wirfs, Week 14

Wirfs is a monster and one of the toughest blockers to get around. Hendrickson will look to help the Ravens get pressure on Baker Mayfield.

Ravens RB Derrick Henry vs. Steelers LB Patrick Queen, Week 15

Henry versus the Ravens' former inside linebacker is always must-see TV. Henry ran by Queen in the 2024 playoffs and he'll be looking to give Queen a taste of his stiff-arm this season.

Ravens G Vega Ioane vs. Browns DT Mason Graham, Week 16

Ioane is the Ravens' new first-round pick. Graham was the Browns' fifth-overall pick in 2025. These two will battle it out for years to come in the AFC North, going a long way in determining who wins in the trenches.

Ravens OLB Trey Hendrickson vs. Bengals LT Orlando Brown Jr., Week 17

Hendrickson will face his former team twice this year, turning practice battles with Brown, a former Raven, into the real thing. Hendrickson's ability to get after Joe Burrow could go a long way in deciding the AFC North winner.

Ravens RT Roger Rosengarten vs. Steelers OLB T.J. Watt, Week 18

Rosengarten has held Watt without a sack against the Ravens over their last three meetings. Can the Ravens' right tackle do it again in Year 3?