QBs Tyler Huntley/Lamar Jackson vs. S Xavier McKinney

Jackson is doubtful to play Saturday night, setting up Huntley to make his second start this season. The veteran backup impressed last week against the Patriots and in his start against the Bears earlier this season, when he completed 17-of-22 passes for 186 yards and a touchdown and gained 53 yards on the ground. Now playing another NFC North team, Huntley will have to be wary of McKinney, who has three interceptions and 10 passes defensed this season.

RB Derrick Henry vs. LB Quay Walker

Henry had another 100-yard effort in last week's loss to the Patriots, finishing with 128 yards on 18 carries and also finding the end zone twice. His second touchdown run early in the fourth quarter was the last time he touched the ball, however. The Ravens will look to get him more involved, especially with Jackson potentially out of the lineup. The Packers have the ninth-best run defense, giving up 103.8 rushing yards per game. Walker has been vital in that effort, leading Green Bay with 116 tackles in 13 games.

ILB Roquan Smith vs. RB Josh Jacobs

Smith just made his fourth Pro Bowl, and deservedly so. Smith has once again been an anchor for the Ravens' defense, leading the unit with 124 tackles. A former first-round pick for the Chicago Bears, Smith has plenty of experience playing in the frozen tundra and will look to continue an impressive stretch for the Ravens' run defense. Jacobs is well on his way to 1,000 yards and is already up to 13 rushing touchdowns this season. With both Packers quarterbacks banged up, Green Bay will rely heavily on Jacobs' legs.

CB Marlon Humphrey vs. WR Christian Watson

Humphrey is tied with Nate Wiggins for a team-high three interceptions this season. Humphrey's ball-hawking ability could come into play Saturday, but he'll also have to be mindful of giving up the deep ball. Humphrey had a tough go against the Patriots last week, surrendering nine catches for 133 yards and a touchdown. Watson is questionable to suit up after missing Thursday's practice with an illness, but assuming he plays, the Packers may try to test the Ravens' secondary.

RT Roger Rosengarten vs. DE Rashan Gary

Rosengarten has had a solid sophomore season, helping pave the way for the No. 3 rushing attack in the league. After racking up 7.5 sacks in his first seven games, Gary hasn't taken down the quarterback in the last eight contests. The former first-round pick remains capable of disrupting offensive game plans, but with Micah Parsons out of the picture, the Ravens' offensive line should be able to gear more attention toward Gary.