RB Derrick Henry vs. ILB Nate Landman

The Ravens' offense has struggled to get into a rhythm since Week 1, and Henry's low production has been a big reason why. Henry has rushed for 50 yards or fewer in the last four games, and with rain in the forecast for Sunday's contest, he could be in store for a heavy dose of rushing attempts. It will be tough to gain momentum against a Rams defense that has yet to give up a run of 20+ yards this season. Landman is second on the Rams with 41 tackles and just had 14 against Christian McCaffrey and the San Francisco 49ers. Landman will aim to have similar numbers against Henry.

CB Nate Wiggins vs. WR Puka Nacua

Wiggins will have a formidable challenge this week, facing the league leader in receiving yards. Nacua has a league-high 52 receptions for 588 yards and two scores. The former fifth-round pick has 10+ catches in four of five games and is the engine that drives the Rams' offense. Keeping him and Davante Adams in check will be critical in getting the defense back on track. If he plays, Marlon Humphrey (calf) could also see a lot of Nacua, considering the Rams star lines up most frequently in the slot.

ILB Teddye Buchanan vs. RB Kyren Williams

Buchanan has quickly found himself as a starter only five games into his rookie season. The fourth-round rookie had the highest Pro Football Focus run defense grade of the team last week, and he'll need to have another performance like that against Williams and the Rams' rushing attack. Williams is sixth in the league with 368 rushing yards and had two receiving touchdowns on eight catches last week. Williams has fumbled nine times in the past three seasons, including twice this year, so he could be a prime target for Buchanan and the Ravens defense to record their first takeaway since Week 2.

LT Ronnie Stanley vs. OLB Jared Verse

Stanley is in line to return to the lineup after missing last week due to an ankle injury. The anchor of the Ravens' offensive front, Stanley will go up against Verse, who leads the Rams with 22 pressures this season, according to Next Gen Stats. Verse and Byron Young, who has a team-high 5.5 sacks, will be eager to hunt down quarterback Cooper Rush.

S Kyle Hamilton vs. QB Matthew Stafford

Hamilton (groin) should be back in the lineup after missing last week's game. The addition of veteran safety Alohi Gilman could free up Hamilton to play closer to the line of scrimmage, where he and Stafford will be up close and personal. Stafford threw for 294 yards and three scores in his last meeting in Baltimore. Two years later, the 37-year-old shows no signs of slowing down, leading the league in passing yards.