The Ravens have completed their roster moves to get down to 75 players by Monday's 4 p.m. deadline.
Linebacker Terrell Suggs (Achilles tendon) and wide receiver David Reed (knee) were both placed on the Physically Unable to Perform (PUP) list.
Linebackers Stevie Baggs (leg) and Darryl Blackstock (leg), safety Emanuel Cook (leg) and defensive tackle Ryan McBean (ankle) have all been placed on injured reserve, ending their 2012 seasons.
To get under the 75-man limit, the Ravens also cut kicker Billy Cundiff, tight end Davon Drew, wide receivers Devin Goda and Patrick Williams, offensive lineman Addison Lawrence, cornerback Jordan Mabin, center Cecil Newton, long snapper Patrick Scales and quarterback Chester Stewart.
By being designated to the PUP list, Suggs and Reed will have to miss at least the first six games of the regular season. They can begin practicing after the sixth week of the season and can practice for up to three weeks before being designated to the active roster, IR or waived.
Both Suggs and Reed have expressed confidence that they will be able to play this season.
Suggs, who suffered the Achilles tendon injury in April, initially said that he expected to be back by November. He has since backed off providing a timetable, but insists he will play at some point during the season.
"I will be in a Baltimore Ravens uniform in 2012," Suggs said at Ravens minicamp in June. "The only question is when."
Ravens Head Coach John Harbaugh also said in a recent chat with fans that he anticipated Suggs would play this season.
Reed went down with a torn ACL on Dec. 24 against Cleveland and he has been rehabbing the injury at the team's facility throughout the offseason. He initially said that he expected to return by training camp, but Harbaugh said at the start of camp that the team would take it slow with his recovery.
When Reed does return, he will be thrown into a tight competition at the wide receiver position and at kick returner.